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Aug 23, 2017 · Applying ultrasound (US) to drug delivery and disease therapy is important work. Sonodynamic therapy (SDT)—a comprehensive therapy using US and a sonosensitizer—exhibits antineoplastic activity in many tumors. In this study, we investigated the feasibility of using a new sonosensitizer (sinoporphyrin sodium, DVDMS) loaded into liposome–microbubble complexes (DLMBs) as a possible ... Sinoporphyrin sodium (DVDMS), a sonosensitizer approved by the FDA, has drawn abundant attention in clinical research, but there are some deficiencies. In order to further improve the efficiency of DVDMS, many studies have applied self-assembly nanotechnology to modify it. Furthermore, the combined applications of …

Apr 18, 2022 · Furthermore, the combined applications of SDT/chemodynamic therapy (CDT) have become a research hotspot in tumor therapy. Therefore, we explored the self-assembly of nanoparticles based on DVDMS and copper to combine SDT and CDT. A cost-effective sonosensitizer was synthesized by dropping CuCl 2 into the DVDMS solution with the assistance of ...

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